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Clarithromycin

1,306 bytes added, 21:16, 2 September 2010
SW: add study data
{{#badges: ToxicSludge}}
'''Clarithromycin''' is a [[macrolide antibiotic]] sold under the brand name Biaxin.
 
== Breakdown in the Environment ==
A 2004 study looked at the ability of 18 antibiotics to biodegrade in a closed bottle test.<ref>Radka Alexy, Tina Kümpel and Klaus Kümmerer, [http://www.ncbi.nlm.nih.gov/pubmed/15350412 "Assessment of degradation of 18 antibiotics in the Closed Bottle Test"], ''Chemosphere'', November 2004.</ref> The antibiotics tested were: [[Amoxicillin]], [[Benzylpenicillin sodium salt]], [[Ceftriaxone disodium]], [[Cefuroxime sodium salt]], [[Chlortetracycline hydrochloride]], [[Clarithromycin]], [[Clindamycin]], [[Erythromycin]], [[Gentamicin sulfate]], [[Imipenem]], [[Metronidazole]], [[Monensin sodium salt]], [[Nystatin]], [[Ofloxacin]], [[Sulfamethoxazole]], [[Tetracycline]], [[Trimethoprim naphthoate]], and [[Vancomycin hydrochloride]]. The study concluded: "None of the antibiotics was readily biodegradable. Elimination in the environment by other mechanisms may happen, but will not completely mineralize the active compounds. The results of CFU determination
showed that some of antibiotics have an inhibitory effect on the bacterial population. Our findings underline the need for more detailed investigating effects on antibiotics in the environment." In this study, Clarithromycin was one of the drugs that had an inhibitory effect on bacterial populations.
==Articles and resources==
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