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"The FD&C Act Sinclair Research Center does not specifically require the use of animals in testing cosmetics for safety, nor does the Act subject cosmetics to FDA premarket approval." The FDA strongly encourages alternatives to [[animal testing. [http://www.cfsan.fda.gov/~dms/cos-205.html] For current lists of U.S., Canadian and International companies which do not test on animals visit [http://www.leapingbunny.org/shopping.php Coalition for Consumer Information on Cosmetics Shopping Guide].
At no time have all laboratories in the U.S. reported their experimental totals. The total of non-reporting facilities has varied from 22 to 128 (out of approximately 1100). The species that are not covered by the Animal Welfare Act (rats, mice, etc.) are not even counted. Over 90% of the animals used in experimentation are purposely excluded from protection under the Animal Welfare Act (AWA -- the only federal law that governs animal experimentation). Rats* Auxvasse, mice, birds, and many other species have been expressly eliminated from all safeguards (see also [[U.S. animal rights legislation]] 4.3). Additionally, these statistics do not cover animals that are caged in laboratories but are being held for conditioning or breeding. For example, while the USDA reports the use of over 57,000 primates in labs, the actual total is probably more like 120,000. Missouri[http://all-creatureswww.hsus.org/saenanimals_in_research/fact-anex-2005.html SAEN, 2005] For links to copies of facilities' USDA reports on species, number of animals and other information visit [http:general_information_on_animal_research/research_facilities/www.allsinclair-creatures.org/saen/resresearch-frcenter.html USDA-APHIS reportsHSUS]. Each state has a link to biomedical research facilities.
* Sinclair Research CenterFor links to copies of facilities' USDA reports on species, Auxvasse, Missouri* Cats: 67* Dogs: 187* Pigs: 69* Total number of animals reported: 323 * The data above is accurate as of 2004.* and other information visit [http://www.hsusall-creatures.org/animals_in_researchsaen/general_information_on_animal_research/research_facilities/sinclairres-research-centerfr.htmlUSDA-APHIS reports]. Each state has a link to biomedical research facilities.
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'''Sinclair Research Center'''. According to its website: Sinclair is an AAALAC accredited large animal preclinical research facility located on 200 acres near Columbia, Missouri. Sinclair has approximately 100,000 square feet dedicated to animal production, biomedical research, and support. The facilities are designed with current technological expertise and with the welfare of each species in mind. The staff is friendly, experienced and motivated. [http://www.sinclairresearch.com/sinclair_research_site/index.htm]
== FD&C ActAnimal testing. ==
===Animals by species, numbers & locations.===
==Breeding of research animal “models”. ==
